Prequel Gleanser Review
BeautyBrief™
Brand
Prequel
Product
Gleanser
Claims check
If you want moisture-conscious cleansing, Prequel's 50% glycerin formula has finished-product hydration testing, but it does not replace medical care or moisturizer.
Shopper fit
- Dry
- Normal
- Combination
- Oily
- Sensitive
- Acne-Prone
Formula flags
- None identified
Shopper preferences
- Vegan
- Cruelty-Free
- Non-Comedogenic
- Dermatologist-Tested
- Hypoallergenic
Key ingredients
| Glycerin | Gives you unusually high humectant support for a rinse-off cleanser. |
|---|---|
| Cocamidopropyl Betaine | Provides gentle foaming and everyday residue removal. |
| Disodium Cocoamphodiacetate | Adds cleansing support while helping keep the wash comfort-focused. |
| Inulin | Adds supporting hydration-focused value. |
| Aloe Barbadensis Leaf Juice | Adds conditioning support in the rinse-off formula. |
Price tier
$$ Mid-Range
Value check
At the Mid-Range tier, you get a large face-and-body cleanser with disclosed 50% glycerin and hydration data, not an exfoliating drug wash.
Where to buy
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Bottom line
If you want a fragrance-free cleanser for face and body, Prequel provides 50% glycerin with product-specific moisture findings. Its sensitive-skin claims do not guarantee tolerance or replace dedicated treatment. At the Mid-Range tier, the value is comfort and versatility.
If you want one fragrance-free cleanser for face and body with unusually strong moisture support, Prequel Gleanser gives you a strong Mid-Range case. The 50% glycerin formula, mild surfactant system, and finished-product hydration testing make the comfort claims more substantial than a typical “gentle cleanser” story.

What it claims
Prequel describes Gleanser as a non-stripping face-and-body cleanser that removes makeup, excess oil, and impurities while maintaining your skin’s natural moisture barrier and pH. The current U.S. page highlights 50% glycerin and says the cleanser is clinically tested to provide moisture for up to 24 hours after use.[1]
The exact product page also identifies it as fragrance-free, hypoallergenic, non-comedogenic, dermatologist-developed, dermatologist-tested, and suitable for sensitive and eczema-prone skin.[1]
Claims vs. formula
Glycerin is the first ingredient and is disclosed at 50%, making moisture support a defining part of the formula rather than a trace claim.
Cocamidopropyl betaine and disodium cocoamphodiacetate provide the cleansing action for everyday oil, light makeup, sunscreen residue, sweat, and routine buildup.
Inulin, dihydroxypropyl arginine HCl, aloe vera, oat kernel flour, glyceryl glucoside, and polyquaternium-10 add more moisture and conditioning support.
Prequel’s product-specific hydration testing supports the 24-hour moisture story more directly than ingredient marketing alone. Its published rosacea-prone-skin study also strengthens the sensitive-skin positioning, but this remains a cosmetic cleanser rather than a rosacea treatment.
Ingredients that matter
Glycerin makes up 50% of this finished formula and appears first in the ingredient list, while cocamidopropyl betaine and disodium cocoamphodiacetate supply gentle foaming. Inulin, glyceryl glucoside, aloe juice and oat flour contribute additional comfort-focused ingredients.
Prequel reports 24-hour moisturization testing and a small clinical study of 30 people with rosacea over five weeks. These are relevant finished-product findings, but they do not make a cleansing product a substitute for medical rosacea treatment or a leave-on moisturizer.
Glycerin
If your skin feels dry or tight, glycerin helps your skin hold moisture. You don't need a high percentage or a separate serum when your moisturizer already works well.
Read the IngredientBriefCocamidopropyl Betaine
Cocamidopropyl Betaine is an established cleansing surfactant and foam booster. Irritation and contact allergy depend on the formula and may involve manufacturing impurities such as amidoamine or DMAPA.
Read the IngredientBriefDisodium Cocoamphodiacetate
Disodium Cocoamphodiacetate is a cleansing surfactant used in micellar waters and face washes. It supports cleansing and skin conditioning, but the full surfactant system determines removal power and mildness.
Read the IngredientBriefAloe Vera
Aloe vera has some human evidence for hydration in specific topical formulas. Aloe juice, extracts, gels, and polysaccharide-rich materials differ, so the finished formula matters more than a headline aloe…
Read the IngredientBriefSafety and regulatory context
Prequel explicitly calls the product fragrance-free, hypoallergenic, non-comedogenic, dermatologist-tested, vegan and cruelty-free on its U.S. product page.[1] Those product-specific declarations justify the corresponding Shopper Preferences but cannot guarantee universal tolerance.
This is the original Gleanser containing 50% glycerin, not Gleanser + SA or Gleanser + Glycolic. The ingredient declaration does not list medicinal exfoliating concentrations, and you should not confuse it with those separate treatment-oriented variants.
What to expect in the short term
You get a fine creamy lather that works on both face and body and removes routine oil, sunscreen residue, light makeup, sweat, and daily buildup without aiming for aggressive degreasing.
If your routine already includes retinoids, exfoliating acids, benzoyl peroxide, or other potentially irritating leave-on products, the fragrance-free formula is easy to fit around them.
What to expect over time
The repeat-use advantage is consistency: Gleanser cleans without asking dry or sensitive skin to trade comfort for foam. The finished-product hydration data strengthen that value case.
At the Mid-Range tier, you are paying for the large face-and-body format, 50% glycerin, sensitive-skin positioning, and product-specific testing rather than treatment actives.
Who it fits
This makes the most sense if your skin is dry, normal, combination, oily, sensitive, or acne-prone and you want a high-comfort cleanser without built-in treatment actives.
The large multipurpose format is especially useful if you want one fragrance-free cleanser for several areas instead of separate face and body washes.
Compare before you buy
Choose Cetaphil Gentle Skin Cleanser when you want a lower-foam facial cleanser with a simpler feel.
Read the BeautyBriefChoose Good Molecules Hydrating Facial Cleansing Gel when a smaller facial-only gel is more useful than Prequel’s face-and-body format.
Read the BeautyBriefFinal Assessment
If your face and body need gentle-feeling cleansing and you prefer fragrance-free formulas, Prequel Gleanser offers unusually high glycerin content and specific hydration testing. That evidence supports the product’s moisture-conscious design without establishing treatment of diagnosed skin conditions. At the Mid-Range tier, its value comes from the generous multiuse format and clear 50% formula disclosure.
Where to buy
Choose a retailer to view current pricing and availability.
We may earn a commission through these links at no additional cost to you.
Last reviewed: October 2026
Sources
Prequel — Gleanser. Official U.S. product and formula details, accessed October 14, 2026.