Sephora Adds Exosome, PDRN, and NAD Skincare From Korean Brands

By Regina Bonham Bordeaux

Several new Korean skincare products at Sephora are putting three science-heavy ingredient stories in front of mainstream U.S. shoppers: exosomes, PDRN, and NAD.

The ingredient names sound advanced, but they do not tell shoppers how much of the material is present, how it is delivered, or whether the finished product itself has been shown to work better.

What launched

THOME’s Exosome Boost Ampoule is a $19 gel ampoule sold at Sephora and designed to be used with the brand’s ultrasound devices. Sephora highlights CICA-EV Exosome, Centella asiatica leaf water, and pantothenic acid and markets the product for redness, blemishes, uneven texture, and barrier support.^[1]

HEVEBLUE’s Salmon Caring Newpair PDRN Booster 100,000 Shot is a 5 mL treatment priced at $19, with PDRN featured prominently in the product name.^[2]

BIOHEAL BOH’s NAD PRIZCELL™ Glow Power Serum is a $34 serum marketed for dullness, uneven tone, uneven texture, firmness, and radiance. Sephora says the formula contains “2,000 NAD capsules” and highlights NAD alongside niacinamide and the brand’s Marix Complex.^[3]

Why it matters

These launches show how quickly ingredients once discussed mainly in research or professional settings are becoming ordinary beauty-shopping language.

For shoppers, the important distinction is between an interesting ingredient story and a proven finished product. “Exosome,” “PDRN,” and “NAD” can refer to very different materials and formulations, so the front label alone is not enough to judge performance.

Exosomes are the clearest example. A 2026 scoping review found limited human evidence for topical exosome skin rejuvenation, along with major differences in exosome sources, delivery methods, and commercial product standardization.^[4]

What we know

These are real U.S. retail launches, and the featured ingredients are central to how the products are being marketed. What the labels do not establish is whether the finished formulas outperform more conventional products aimed at the same concerns.

That means the complete formula still matters: delivery system, tolerability, usability, price, and finished-product evidence all count more than the ingredient name by itself.

What we’re watching

For exosomes, clearer sourcing, characterization, and finished-product testing will matter as more products reach mainstream retailers.

PDRN and NAD deserve the same scrutiny. A scientifically interesting ingredient is a reason to look more closely at a product—not a reason to assume it works better.